刚下了avastin官网的用药指南:* h2 G9 I1 I% d9 P) B9 B' h
& ^4 |+ t& d( [4 J9 [" V' ?" K Patients should continue treatment until disease progression or unacceptable toxicity. " @5 J9 a- }$ \5 A
1 Metastatic Colorectal Cancer (mCRC)
0 n. F- g; Q7 r4 l# E. r( c The recommended doses are 5 mg/kg or 10 mg/kg every 2 weeks when used in combination with
5 F1 I1 m4 I$ Iintravenous 5-FU-based chemotherapy.
$ o( o! k) O' ?0 q+ _% d, Y• Administer 5 mg/kg when used in combination with bolus-IFL. - F5 r. E* v" C3 ^6 j- k9 I
• Administer 10 mg/kg when used in combination with FOLFOX4.
& n+ @. O8 F( J2 Non-Squamous Non-Small Cell Lung Cancer (NSCLC) # d# R' q4 ?* b3 P# ~% W0 Y; a5 l" j
The recommended dose is 15 mg/kg every 3 weeks in combination with carboplatin and 2 I' a. |; {1 q5 g! {
paclitaxel. 1 }! G! o6 z" b2 N" b
3 Metastatic Breast Cancer (MBC)
# h) K* x) a' Z. ~ The recommended dose is 10 mg/kg every 2 weeks in combination with paclitaxel.
2 O, z# o' c- y$ R$ f( H' _4 Glioblastoma
- A3 T/ H, {! ] The recommended dose is 10 mg/kg every 2 weeks.
/ v2 G, O9 U% }6 d! {/ b5 {5 Metastatic Renal Cell Carcinoma (mRCC)
! y0 b+ T+ j$ _9 d1 O G2 c( R; W The recommended dose is 10 mg/kg every 2 weeks in combination with interferon alfa. ) d) \" {0 ` g7 l: c' O
, d# {5 j; ~- n2 _/ |: H2 N
按照这个说明非小细胞腺癌的服用剂量是15mg/kg,与卡铂紫杉醇合用,avastin每三周用一次。8 z; w( w$ H* @/ R% w, ?# C: Q5 w
我妈妈是肺腺癌转肝,体重53kg,现在医生联合卡铂紫杉醇化疗了一个疗程21天。 但avastin不是一次注射的,每7天注射一次200mg,一个疗程21天注射了3次(分别是第一、八、十五天) |